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I literally went to every doctor i could to try to figure out what was wrong with me. Little did I know it would be a terminal cancer called multiple myeloma. #cancer #myeloma #blood #bloodcancer #doctor
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MULTIPLE MYELOMA: Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. In MM, the abnormal plasma cells produce abnormal antibodies, which can cause kidney problems and overly thick blood. The plasma cells can also form a mass in the bone marrow or soft tissu
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Answers (if you’re doing the UKMLA this year there’s a little something at the end of the caption for you) Pathophysiology of myeloma Malignant clonal proliferation of plasma cells in the bone marrow Production of monoclonal immunoglobulin (paraprotein/M-protein) and/or free light chains, causing immune paresis and increased infection risk End-organ damage via multiple mechanisms: Bone destruction: Plasma cells secrete cytokines (IL-6, MIP-1α) → increased osteoclast activity and decreased osteob
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