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Is Variolation Different From Modern Vaccination?
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“In Asia, practitioners developed the technique of variolation—the deliberate infection with smallpox. Dried smallpox scabs were blown into the nose of an individual who then contracted a mild form of the disease. Upon recovery, the individual was immune to smallpox. Between 1% to 2% of those variolated died as compared to 30% who died when they contracted the disease naturally. By 1700, variolation had spread to Africa, India and the Ottoman Empire. In contrast to Asians and Africans who inocul
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