Cascades: Consider a cascade of three activators, X →Y →Z. Protein X is initially present in the cell in its inactive form. The input signal of X, Sx, appears at time t=0. As a result, X rapidly becomes active and binds the promoter of gene Y, so that protein Y starts to be produced at rate β. When Y levels exceed a threshold Kf, gene Z begins to be transcribed. All proteins have the same degradation/dilution rate α. What is the concentration of FIGURE 1.13 Adapted from (Rosenfeld and is its res
Cascades: Consider a cascade of three activators, X →Y →Z. Protei…
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