The Cardinals open on the road and end the season with two consecutive road games. They have two prime-time games scheduled. They have their bye week in Week 8. In 2025, as an odd year, the entire NFC will have eight home games and nine road games. The AFC will have nine home games and eight road games.

Arizona returns to prime time this season with a Monday night game against Dallas in Week 9. It'll also be on Thursday Night Football for the first time since 2022, when it plays Seattle in Week 4. The Cardinals' revamped defense will be tested throughout the season, as it will face seven former No. 1 picks and four Heisman Trophy winners.

The Arizona Cardinals finished last season with an 8-9 record, marking their first time topping four wins in two years.

The Arizona Cardinals promised a banger for the 2025 NFL schedule release video and unlike last year, the Cardinals weren't late to the party. As all 32 NFL teams release their schedules on Wednesday,

The Arizona Cardinals' 2025 regular season schedule was released this week. Here's where to buy tickets for all the games.

The Arizona Cardinals will release their full 2025 regular-season schedule at 5 p.m. Arizona Cardinals, but we have some information. We know they will open the season on the road against the New Orleans Saints.

“The combine record for the following opponent was 132-157 last year, 27th in the NFL in terms of strength of schedule in 2025. The Cardinals are tied with Carolina Panthers with a .457 winning percentage for their opponents next year,” Tanner Tortorella wrote.