To help you make them, here's a look at five players with bust potential in Week 6. Something to keep in mind as you're ...

Brock Purdy and the 49ers’ defense look to create another clutch win in Seattle Thursday night against the Seahawks.

The San Francisco 49ers will play the Seattle Seahawks in a game that could determine both teams’ seasons. Colin Cowherd discusses Brock Purdy’s performance this year and why this game is so important ...

Kirk Cousins and Caleb Williams are among UPI senior sports writer Alex Butler's five must-start fantasy football ...

James Jones explains why Brock Purdy is under more pressure than Kyle Shanahan against the Seattle Seahawks on Thursday Night ...

This 49ers vs. Seahawks betting preview features the Week 6 Thursday Night Football game's latest odds, team analysis, and ...

At Lumen Field on Thursday, Jordan Mason and the San Francisco 49ers play Geno Smith and the Seattle Seahawks in a battle ...

Week 6 in the NFL kicks off from Lumen Field as the Seattle Seahawks are set to host the San Francisco 49ers in an NFC West ...

See our best NFL prop picks for Week 6, starting off with Brock Purdy odd against the Seattle Seahawks on Thursday Night ...

The San Francisco 49ers are 2-3, heading into "Thursday Night Football" with the Seattle Seahawks. Here's how to watch the game on Amazon Prime Video.

This year, the 49ers put up just 2.4 more points per game (25.2) than the Seahawks surrender (22.8). This year, the 49ers ...

Tom Brady made a stark admission about the 49ers star in the Fox Sports broadcast booth leading up to Thursday's 49ers game ...