Background Heart auscultation is a widely used and cost-effective clinical tool for detecting valvular heart disease (VHD), ...

Background Chronic kidney disease is common in patients with coronary artery disease (CAD) and can significantly affect drug excretion and efficacy. This study focuses on the effects of modification ...

Background Current risk scores inadequately predict long-term mortality after transcatheter aortic valve replacement (TAVR), ...

Objective Implantable cardioverter defibrillators (ICD), cardiac resynchronisation therapy pacemakers (CRT-P) and the combination therapy (CRT-D) have been shown to reduce all-cause mortality compared ...

Objective Frequent flares of pericardial inflammation in recurrent or incessant pericarditis with corticosteroid dependence and colchicine resistance may represent a risk factor for constrictive ...

Objective To evaluate the association between chocolate intake and incident clinically apparent atrial fibrillation or flutter (AF). Methods The Danish Diet, Cancer, and Health Study is a large ...

Currently, most international guidelines advocate for risk stratification of acute pulmonary embolism (PE) as a framework to guide treatment decisions. Key prognostic factors for patients with PE ...

Comparative evaluation of biological and mechanical prostheses for aortic valve replacement in a middle-aged population: a population-based cohort study ...

Atrial fibrillation is increasingly encountered in patients with heart failure. Both diseases have seen tremendous rises in incidence in recent years. In general, the treatment of atrial fibrillation ...

Introduction Epicardial adipose tissue (EAT) exerts paracrine effects on the myocardium. More lipid-laden adipocytes, with lower attenuation on computed tomography (CT), are associated with greater ...

Clinical introduction A 49-year-old man presented to the emergency department following sudden onset chest pain with collapse. He was refurbishing his home when he collapsed on the floor with chest ...

Coronary disease mortality, incidence, and clinical presentation vary greatly over time. In many countries with a high prevalence of coronary heart disease, mortality is now falling rapidly. 1–4 ...