When it comes to weight loss, there are a number of tried and true lifestyle changes you can make to help you along the way.

The Best Time to Take Metformin It’s super important to follow your healthcare provider’s instructions on how to take your version of metformin. The rule of thumb is to start low and adjust ...

For many people, the worst gastrointestinal effects of metformin begin to improve over time. Dr. Vora says that the drug is effective, safe, and inexpensive, so it might be best to stick with it ...

Metformin made most of them more active, but only if Rap1 was present. In mice lacking Rap1 in these neurons, metformin had no effect, showing that Rap1 is essential for metformin to “switch on” these ...

Patients with knee osteoarthritis who received metformin demonstrated significant reductions in knee pain and increased weight loss at 6 months vs. placebo, according to data published in JAMA ...

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential ...

Continuing metformin after bariatric surgery did not provide additional benefits for glycemic control or weight reduction in patients with obesity and type 2 diabetes, a retrospective study found.

Dear J.H.: Metformin, a treatment for diabetes that works mostly by preventing the liver from making sugar, isn't new and has been used to help people lose weight for at least 20 years.