A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
Chemical structure of imatinib, a precision cancer drug containing an amide bond. Xiaoguang Lei and his team used their engineered enzyme to streamline the synthesis of imatinib, a landmark cancer ...
A new reaction cuts nitrogen atoms out of secondary amines with surgical precision. The transformation offers a route to strained structures, such as cyclobutanes (example shown), that can be ...
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