An international research team from Bielefeld University and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP ...

Researchers have discovered that lysosomes, traditionally viewed as cellular waste bins, sense mechanical forces and reposition themselves to the cell's edge to trigger the formation of leader cells ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down defective ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

New research, published today in the journal Science, shows how lysosomes — organelles that act like cells’ waste disposal system — respond to stress by becoming abnormally bloated, a process called ...

C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...