It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...
The Suzuki-Miyaura reaction, which uses a base and a palladium catalyst to make new carbon-carbon bonds, is one of the most widely used coupling reactions in industrial chemistry. By simply swapping ...