Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

The positions of these water molecules are often important for understanding protein flexibility and the ability of drug-like molecules to influence protein structure and function. In this study, ...

Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Solving puzzles experimentally is enjoyable for many researchers. However, there are some puzzles that force even the best puzzlers to nominate modeling over experimental approaches to help decipher ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases. Proteins do the heavy ...