Scabies is a skin infestation caused by the mite Sarcoptes scabiei and represents a substantial global health burden exacerbated by emerging resistance to ivermectin. An anionic pentameric ...
At pH 8, each PAC protomer adopts an arm-like structure, with the ECD as the hand, the ECD–TMD interface as the wrist and the TMD as the forearm (Extended Data Fig. 4e). The hand-like ECD is composed ...
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