The dynamic clamp method was introduced independently by Robinson and Kawai 1 and Sharp et al. 2 Initially it was used to introduce artificial conductances into neurons to mimic the effect of ...

Flip-the-Tip Technology Uses Standard Glass Pipettes to Achieve Higher Throughput in Ion Channel Screening The pharmaceutical industry has widely recognized patch clamping as the “gold standard” to ...

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...