Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory ...

A first-in-class nanoparticle injection sneaks antibodies into pancreatic cancer cells to clear mutant KRAS, shrinking tumors ...

A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to ...

Mutations of KRAS have long been targets of interest for the development of new cancer therapies, but structural changes caused by these mutations have made it particularly difficult to target and ...

TheFly reported on June 17 that VSTM Oncology announced updated safety and efficacy findings from the RAMP 205 Phase 1b/2a ...

Share on Pinterest New research shows certain KRAS mutations in pancreatic cancer may improve survival rates compared to other mutations. William Taufic/Getty Images In 2020, more than 495,000 adults ...

Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval. According to the National Cancer ...

Few stories in oncology have evolved as dramatically as that of KRAS. For nearly four decades, KRAS has been regarded as the quintessential “undruggable” protein: an elusive molecular target whose ...

July 6, 2012 — The US Food and Drug Administration (FDA) has approved the therascreen® KRAS RGQ PCR Kit to be sold as a companion diagnostic test for cetuximab (Erbitux). In addition, the FDA has ...

Researchers at the University of Cologne's Center for Molecular Medicine Cologne (CMMC) have discovered a previously unknown ...

Colon cancer used to be treated the same way for almost everyone. That’s no longer true. Today, doctors are increasingly looking at the genetic makeup of each patient’s tumor to guide treatment ...

A late-stage trial found a new pill, daraxonrasib, doubled median survival and improved quality of life, compared with ...