Structurally, they look similar: MNK1 and MNK2 belong to the same enzyme family and are best known for regulating how cells ...
Protein kinases comprise one of the largest families of evolutionarily related proteins. Mutations in kinase genes underlie many human diseases, particularly developmental and metabolic disorders, as ...
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signalling and trafficking. Its kinase activity ...
A new study reveals that the twin enzymes MNK1 and MNK2 play distinct roles in the brain, with one governing memory and the other social behavior.
BACKGROUND: BCR-ABL tyrosine kinase inhibitors (TKIs) have been increasingly linked to pulmonary arterial hypertension (PAH) since 2009, although supporting evidence is limited. Our objective was to ...
The discovery of phosphatidylinositol 3-kinase (PI3K) changed the way we view and understand growth-factor signaling. From early on, it became clear that PI3K plays an important role in many disease ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results