Novel nephron organoids that can be fine-tuned to represent the proximal convoluted tubule or loop of Henle have been ...
In videos created by the Hughes Lab to visualize the process, adjacent nephrons form one after the other, as if they were following a beat. “It’s still a hypothesis,” adds Hughes, “but we think that ...
A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...
When the kidneys are damaged—after surgery, cardiac arrest, or as a side effect of certain medications—doctors often face one ...
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Stem cell studies detail how progenitor cells self-renew, differentiate and aggregate into early kidney structures
A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its ...
For most children with renal masses, the standard of care has long been to remove the entire affected kidney- which is the protocol for Wilms tumor, the most common kidney cancer in children. But is ...
A scoring criterion which can distinguish between benign and malignant tumors in pediatric patients with renal masses could help determine if they can benefit from partial rather than radical ...
A recent inspection at a South Carolina drug production facility flagged several problems with how the company was producing drugs for the mass market, little more than a year after the same facility ...
1. Huang J. Disitamab vedotin plus tislelizumab as nephron-sparing therapy for high-risk upper tract urothelial carcinoma: The phase II DISTINCT-I trial. Presented at: ESMO 2025 Congress; October ...
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