Small metal ions such as iron are necessary cofactors for many enzymes, and iron-containing enzymes play multiple roles in cellular processes. Therefore, iron is an essential nutrient, and iron ...

Ferroptosis is a regulated form of cell death characterised by iron-dependent lipid peroxidation and distinct from apoptosis or necroptosis. In the retina, precise control of iron uptake, storage and ...

In a recent study published in Nature Communications, researchers demonstrated a magnetic resonance imaging (MRI) method sensitive to the live brain's iron homeostasis (the r1-r2 extent of relaxation ...

A new research paper titled "Targeting of FSP1 regulates iron homeostasis in drug-tolerant persister head and neck cancer cells via lipid-metabolism-driven ferroptosis" has been published in Aging.

If a woman experiences chronic stress late in her pregnancy, it can affect her fetus' ability to absorb iron by as much as 15%, according to a study led by UW Medicine researchers in Seattle. In a ...

A model of Fe homeostasis regulation by MdCML15–MdBT2–MdbHLH104–MdAHA8 in apple trees. When apple roots are exposed to Fe-sufficient conditions, MdCML15 is induced to interact with MdBT2 in the ...

Hematopoietic stem cells give rise to all blood cells in the body. Most of the time they are not dividing. Rather, they serve as a reserve for the times when the body needs rapid blood formation. “One ...

In a study published in PNAS, researchers from the Xishuangbanna Tropical Botanical Garden (XTBG) of the Chinese Academy of Sciences have clarified the molecular mechanism underlying the roles of IRON ...