A new article in the peer-reviewed journal Nucleic Acid Therapeutics describes the characterization of antibodies targeting antisense oligonucleotide (ASO) phosphorothioate and 2'-methoxyehtyl ...

The process of GLUT4 trafficking is central to the metabolic regulation of blood glucose levels. In both muscle and adipose cells, the insulin hormone triggers the mobilisation of intracellular ...

Michigan State University postdoctoral researcher Deepak Bhandari explores the molecular logistics of plant immunity and the ...

Peptide conjugation techniques are advancing CNS delivery of oligonucleotides, addressing blood-brain barrier challenges and ...

This study revealed two independent retrograde pathways: a sorting nexin–mediated pathway (orange) and a core retromer–mediated pathway (blue). In yeast, sorting nexins and the core retromer form a ...