Nicotine's effects (and how long they last) depend on many variables Medically reviewed by Armeen Poor, MD Nicotine stays in your body for different amounts of time depending on the type of test.

Nicotine has a half-life of about two hours and can stay in the blood for about one to three days. Cotinine, a byproduct of nicotine, has a half-life of 18 hours and can last for several days.

How the tobacco industry rebranded a brutally addictive drug from deadly to desirable—and what it means for our health.

Men's Health debunks common nicotine health hacks, from improving cognition to boosting T levels to protecting us from ...

We asked a few guys how they kicked their nicotine addiction—and what life is like on the other side of Zyn. This piece is ...

From improvements to your skin to a lower risk of heart disease happens to your body in the hours, days, weeks and months after you give up cigarettes.