There’s an old joke that you can’t trust atoms — they make up everything. But until fairly recently, there was no real way to see individual atoms. You could infer things about them using X-ray ...

Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts. It is caused by a mutation in ...

SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely ...

The structure of a transport complex used by bacteria to import aspartate has been mapped in unique detail by University of Groningen scientists. The proteins were imaged using cryo-electron ...

The first molecular-level structural analysis of the Omicron variant spike protein in complex with human ACE2 is now available. The near-atomic resolution analysis—using cryo-electron ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

A new era in structural biology is coming to UC Davis, and it is already yielding discoveries. It’s called cryoelectron microscopy, or cryo-EM, and it allows biologists to capture three-dimensional ...

image: Sixty fusion proteins of a pentameric Sm-like protein (PDB ID: 3BY7) and a dimeric MyoX-coil domain (PDB ID: 2LW9) self-assemble into a protein nanoparticle complex, TIP60 (Truncated ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...