Dendritic cells occupy a pivotal role at the nexus of metabolism and immune regulation, employing distinct bioenergetic programmes to calibrate antigen uptake, processing and presentation. In their ...

Researchers at the Icahn School of Medicine at Mount Sinai have identified the immune cell that acts as the architect and coordinator of powerful immune hubs that form inside tumors and plays a key ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial checkpoint that enables dendritic cells to efficiently activate T ...

Dendritic cells (DCs) in teleost fish are pivotal antigen-presenting cells that bridge the innate and adaptive arms of immunity. Morphologically and functionally analogous to their mammalian ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

Artistic rendering of a human dendritic cell. (Don Bliss & Sriram Subramaniam/National Cancer Institute) While it's also produced naturally by the body, creatine is perhaps best known as a 'muscle ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body’s key cancer-fighters, ...

A popular workout supplement was linked to a surprising effect on cancer.

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...