Early in the pain process, newly generated neurons in the dentate gyrus showed increased activity – suggesting the brain initially mounts a protective response to persistent pain. Over time, however, ...

Young people with chronic pain also have higher rates of depression and anxiety, according to a systematic review and meta-analysis. In an analysis of 79 studies totaling almost 23,000 youth, the ...

Four in ten adults with chronic pain experience clinically significant depression and anxiety, reported a new systematic review and meta-analysis published in JAMA Network Open. "Right now, we have ...

Poster findings presented at AAPM PainConnect 2026 showed that new-onset postoperative depression increased risk for chronic postsurgical pain.

The combination of preoperative opioid use and depression increased postsurgical risk for chronic postsurgical pain and persistent opioid use.

Depression and anxiety affect approximately 40% of adults with chronic pain, according to a massive new systematic review and meta-analysis published in JAMA Network Open. The comprehensive study ...

The investigators identified a total of 376 relevant studies from 50 countries, including 347,468 individuals (70% of whom were female) with chronic pain. The pooled prevalence rates for depression ...

Of those with chronic pain in a recent study, 34.6% had anxiety diagnoses and 12.2% had depression diagnoses. HealthDay News — Among youth with chronic pain, a number of individuals are diagnosed with ...

A novel analysis of more than 375 published studies concluded that the association between chronic pain and rates of ...

Chronic pain has long been known to be associated with depression. Among adults with chronic pain, around 40% exhibit clinical symptoms of depression. But why is it that only some people with chronic ...

Large population data from Iran show that body weight and iron intake help statistically explain the depression–headache link, while physical activity plays a supporting, indirect role rather than a ...