Understanding calcium signals and their spatiotemporal regulation in complex tissues and organs is crucial for research on basic cell and organ function, disease states and for the development of ...

Mitochondria are crucial for maintaining calcium balance in cells, but their calcium dynamics are challenging to study due to pH changes in the mitochondrial matrix, and the lack of cyan-colored GECIs ...

DEAR DR ROACH: I am a 60-year-old female. I was diagnosed with primary biliary cholangitis (PBC) in 2020. At the time, I had a bone density scan that showed osteopenia of the left femoral neck with a ...

Mitochondrial calcium signaling is crucial for energy metabolism and calcium homeostasis, but monitoring it accurately is challenging due to pH fluctuations. Existing GECIs are often sensitive to pH ...