Researchers at Texas A&M Health and collaborators have developed engineered CRAC channel inhibitory binders that can ...

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...

Dear Dr. Roach: My doctor put me on Norvasc 10 mg to keep my blood pressure normal. Since Norvasc is a calcium-channel-blocking medicine, can I still take my calcium and vitamin D-3 supplements? I was ...

Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such ...

When three bright minds from different disciplines come together, something exceptional can happen. This is exactly what Prof. Patricia Hidalgo, Dr. Beatrix Santiago-Schübel, and Dr. Mercedes ...

Sphingolipids are ubiquitous components of membranes and function as bioactive lipid signaling molecules. Here, through genetic screening and lipidomics analyses, we find that the endoplasmic ...

A subunit of voltage-gated calcium channels was found to have a functional role in T-cells, according to a Northwestern Medicine study published in Nature Communications. The findings add to a growing ...

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...

Eczemas in the elderly often arise mysteriously and itch furiously. New-onset, otherwise unexplained eczema that cannot be attributed to atopic disease, irritant or allergic contact dermatitis, or ...

Lysosome malfunction caused by an organelle's inability to clear lipids or other waste from the cell plays a central role in lysosomal storage diseases (LSDs). Though those diseases have disparate ...

A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an ...

The kidney plays a pivotal role in regulating calcium levels within the body. Approximately 98% of the filtered calcium is reabsorbed in the nephron, and this process is tightly controlled to maintain ...