Current approaches for protein–nucleic acid complex structure prediction involve building models of the protein and nucleic acid (NA) components separately and then building up complexes using ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...

Protein-ligand docking is an established tool in drug discovery and development to narrow down potential therapeutics for experimental testing. However, a high-quality protein structure is required ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta ...

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...