Appearing on Asante Samuel's podcast "Say What Needs To Be Said," Sanders found himself suddenly dodging personal questions rather than defensive backs. When Samuel asked about Tran, who had been seen accompanying Sanders during his highly publicized hospital visits related to recent health challenges, Sanders quickly employed a comedic tactic.

Karrueche Tran’s emotional response as she waited with NFL legend Deion Sanders for him to have surgery for bladder cancer has caused speculation that the pair are dating.