Oddsmakers project the San Francisco 49ers (6-10) to put up a fight in their attempt to break their three-game losing streak, as they are just 4.5-point underdogs in a matchup with the Arizona

This NFC West showdown features a matchup between two disappointments. The San Francisco 49ers were expected to compete for a Super Bowl, yet they trot into the final week of the regular season with a measly six wins.

Unlike the Arizona Cardinals, the Los Angeles Rams have plenty to play for in Saturday night's game at SoFi Stadium. There's a chance the Rams can clinch the playoffs this weekend with a win over the Cardinals and help from four other teams on Sunday.