The Bucks’ biggest challenge this season will be regaining the defensive edge they had under Mike Budenholzer, who was fired after a shocking first-round playoff exit to the Miami Heat. Budenholzer led the Bucks to a 58-24 regular-season record and finished fourth in defensive efficiency (110.9 points allowed per 100 possessions).

The Milwaukee Bucks and Philadelphia 76ers open their seasons Wednesday. Tip-off from Wells Fargo Center is scheduled for 7:30 p.m. ET (ESPN). Let's analyze BetMGM Sportsbook's

SportsLine's model just revealed its NBA picks and predictions for the Milwaukee Bucks vs. Philadelphia 76ers game on Wednesday

Damian Lillard scored 30 points while leading the Milwaukee Bucks to a 124-109 road win over the Philadelphia 76ers on Wednesday night in the season opener for both teams. Giannis Antetokounmpo contributed 25 points on 8-of-11 shooting to go along with 14 rebounds and seven assists for Milwaukee.

Damian Lillard scored 30 points, Giannis Antetokounmpo added 25 and the Milwaukee Bucks defeated the Philadelphia 76ers 124-109 in the season opener for both teams Wednesday night. Lillard scored 15 points in the third quarter and finished with six 3-pointers,

Damian Lillard (30 points, 6 3PM, 9 rebounds, 6 assists) and Giannis Antetokounmpo (25 points, 14 rebounds, 7 assists) combined for 55 points as Bobby Portis and Taurean Prince added 17 points each. Tyrese Maxey was 10-31 from the floor for 25 points,